Five compounds. Clinical doses. No proprietary blends.

CortiCore is a cacao-based morning powder. Five botanicals, each at the dose used in the published clinical research, and a short list of supporting ingredients. The full supplement-facts panel is below.

The five active compounds

Ashwagandha (Withania somnifera) — KSM-66 · 600 mg

Standardized full-spectrum root extract from Ixoreal Biomed. The most extensively studied ashwagandha standardization, used in over two dozen published human trials on cortisol, sleep, and stress markers.

Saffron (Crocus sativus L.) — Affron · 28 mg

Standardized stigma extract from Pharmactive. Studied in clinical trials of perimenopausal mood symptoms and vasomotor episodes. The 28 mg dose matches published trials of menopausal women.

Lion’s Mane (Hericium erinaceus) — Full-spectrum · 750 mg

Whole fruiting-body extract, not mycelium-on-grain. Standardized for beta-glucans and hericenones, the compounds linked to the cognitive endpoints in published research.

Rhodiola Rosea — SHR-5 · 300 mg

The standardized root extract used in the Swedish HPA-axis fatigue trials. Pulled into the formula to address the afternoon energy slump that follows a cortisol spike.

Maca (Lepidium meyenii) — Gelatinized · 2 g

Gelatinization removes the raw starches that make some women bloat from non-processed maca. The 2 g dose anchors the formula’s hormone-support arm alongside the cortisol-targeting actives.

All five active extracts are tested for identity, potency, heavy metals, microbial contamination, and pesticide residues by an ISO-17025 accredited third-party lab. Certificates of analysis available on request to support@menoreign.com.

Supporting ingredients

• Cacao powder (organic, fair-trade) for the chocolate flavor base.
• Monk fruit extract for a small amount of natural sweetness. No sugar, no stevia.
• Coconut milk powder for creaminess when mixed with water.
• Cinnamon (organic) for warmth.
• Himalayan pink salt in trace amounts to round the cacao.

What is not in CortiCore

• No added sugar. No high-fructose corn syrup. No artificial sweeteners (no stevia, no sucralose, no aspartame).
• No soy, dairy, gluten, eggs, peanuts, tree nuts, or shellfish.
• No proprietary blends. Every active compound is labeled with its exact milligram dose.
• No fillers, no artificial colors, no synthetic flavors.
• Non-GMO. Vegan. Gluten-free.

Sourcing & manufacturing

CortiCore is blended, packed, and tested in a U.S. cGMP-registered facility in compliance with FDA 21 CFR Part 111 for dietary supplements. Each batch carries a lot number and expiration date on the bottom of the pouch.

Disclaimer. These statements have not been evaluated by the Food and Drug Administration. CortiCore is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. If you are pregnant, breastfeeding, under 18, or taking prescription medication, consult your physician before use.

Questions about an ingredient, source, or COA? Email support@menoreign.com and we will reply within one business day.